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| | Dose Of News Useful TodayTuesday, April 14th |
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| Good morning. A big thank you to everyone who participated in yesterday’s contest, and congratulations to our winner, Ann. To those of you who just missed out, never fear! We’ll be doing another giveaway soon. In the meantime, you can get $50 worth of free delivery food (and much more) by referring people to the DONUT. Just check the bottom of this email for instructions. |
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Daily Sprinkle | “Success is not final, failure is not fatal: it is the courage to continue that counts.” - Winston Churchill |
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 | The Crusade For A Cure | Global cases of COVID-19 rose to nearly 1.93 million yesterday with almost 120,000 deaths. More than one-third of the world’s population is currently under some form of restriction as scientists work to develop a treatment for the virus. A Shot In The Arm According to the WHO, there are currently 70 potential COVID-19 vaccines in development, with three having reached the human clinical trial stage. - The furthest-along candidate belongs to the Beijing Institute of Technology and CanSino Biologics, which Bloomberg reports has already entered phase 2 human clinical trials.
- Moderna is currently in phase one human trials with their candidate, which - if proven safe and effective - could be deployed in as soon as 12 months.
- Inovio Pharmaceuticals (backed by the Bill & Melinda Gates Foundation) last week began phase one human clinical trials on their vaccine candidate.
Treat Yo’ Self More than a dozen other companies are attempting to repurpose existing treatments that have been proven safe for humans to instead fight COVID-19. - Pharma giant Gilead last Friday published a limited - but promising - case study of its failed Ebola drug remdesivir, with more thorough testing data due in May.
- The National Institute of Health began enrolling participants in a human clinical trial of malaria drug hydroxychloroquine on April 3. Evidence of its effectiveness thus far has been conflicting, and studies of the drug in Brazil and France also showed heart complications in patients.
- Regenaron last week said it was “a couple weeks or a month” away from releasing clinical trial data from its arthritis drug Kevzara. A similar arthritis drug called Actmera (developed by Roche) last week received a $25 million government grant to conduct phase 3 clinical trials.
That’s A Wrap... But before you go further down the newsletter, here are a few positive coronavirus-related stories to give you a brief respite from the doom and gloom: |
| | Toddler Comforts Terrified Golden Retriever When Thunderstorm Hits | Inspire More | Drive-by Strauss: Hungarian orchestra airs concerts from cars | The Guardian | Baseball is Back: Some Good News with John Krasinski Ep. 3 | YouTube | Google partnering to give cash to 5,000 families; Pichai donates $1m | CNBC |
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 | Coronavirus UpdateThe number of confirmed U.S. cases rose to more than 587,000 with 23,644 confirmed deaths. - Treasury Secretary Steven Mnuchin on Monday said more than 80 million Americans will receive their stimulus direct deposits by Wednesday (Here's everything you need to know about the stimulus payments).
- The FDA has granted emergency use authorization for a saliva-based coronavirus test developed by a Rutgers University-backed entity.
- Both western states (CA, OR, WA) and eastern states (NY, NJ, CT, PA, RI, DE) have formed separate coalitions to coordinate eventual easing of economic restrictions.
- The FDA on Monday granted emergency use authorization for a process of decontaminating N95 masks that can potentially clean up to four million masks per day.
- Wyoming reported its first coronavirus death on Monday. All 50 U.S. states have now seen at least one death.
- The Supreme Court announced plans to hear oral arguments by teleconference in May due to coronavirus. The arguments cover several major cases, including President Trump’s financial disclosures and an electoral college issue.
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Sanders Endorses BidenBernie Sanders officially endorsed presumptive Democratic presidential nominee Joe Biden on Monday, five days after Sanders suspended his campaign. The endorsement comes as Biden was declared the winner of Wisconsin’s April 7 primary, where in-person voting was held following a controversial State Supreme Court decision. | |
Food Shortages After Locust InvasionSwarms of locusts have damaged 500,000 acres of crops in Ethiopia, leaving roughly one million people in need of emergency food aid. One of the region’s wettest rainy seasons in decades has led to swarms of locusts - sometimes covering areas as large as 1,000 sq. miles - that have traveled across much of Eastern Africa. More: According to the UN, an even more massive second wave of locusts have begun to invade Africa from their breeding grounds in Somalia, with estimates of up to 20 times more damage. | |
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 | The Coronavirus Effect- Shares of Netflix reached a 52-week high Monday, as fellow media company Roku’s shares rose more than 9% in after-hours trading after promising revenue projections.
- A new report predicts a 40% year-over-year decrease in U.S. box office numbers, with the projected $6.6 billion representing the lowest number since the late 1990s.
- PayPal, Intuit, and Square recently became the first fintech companies to receive approval to participate in the U.S. government’s $350 billion small business loan program.
- About two million homeowners are reportedly skipping their monthly mortgage payments. The recent stimulus package allows homeowners to request forbearance without penalty for up to 12 months.
- Amazon will allow third-party sellers on its platform to resume shipping non-essential items - in a limited capacity - starting later this week.
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Hindsight Is 20/20SoftBank on Monday said it expected to record a loss of 1.8 trillion yen (~$17 billion) in its Vision Fund over the fiscal year just ended. These new reported losses mean the $100 billion fund is likely down overall since its inception three years ago, though the company said the latest results may change as the numbers are finalized. More: Of the Vision Fund’s seven largest investments, three are ride-sharing companies (including Uber and Chinese counterpart Didi Chixung) who have seen business all but shut down recently due to coronavirus. | |
Quibi’s QuotaQuibi CEO Meg Whitman on Monday said the mobile app had seen 1.7 million downloads in its first week of availability. Whitman also said the company would prioritize making Quibi videos available to cast from phones to TVs in light of more people staying at home due to coronavirus. | |
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 | Beer Here!While some people are finding it hard to stay occupied during the extended quarantine, 93-year-old Olive Veronesi seems to be holding up just fine - as long as she’s fully stocked with beer. An image of Olive behind glass doors holding a sign that said “I Need More Beer!!” recently went viral, and was used by local Pittsburgh news affiliates as an example of proper social distancing. | |
The Masked SwingerThe extended period of quarantine has been hard on everyone, but it can be especially hard for young kids who have been cooped up without direct access to their friends. Two men from London, England have taken it upon themselves to cheer up their young neighbors by dressing up in a full Spiderman costume before going outside for their hour of daily exercise, providing entertainment to kids around the block | |
Where In The World Is Brandon Smith?Twelve-year-old Brandon Smith usually celebrates his birthday with a father-son adventure, but this year his dad, Jody, was forced to improvise due to the coronavirus pandemic. Brandon is a geography enthusiast, so Jody had his son draw a map of the world. Then, Jody took to Twitter asking for replies from as many different locations as possible, with Brandon marking off each place as they came in. Jody’s post garnered thousands of responses aimed at making Brandon’s birthday an adventure he won’t soon forget! | |
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 | Browsing History | In what year was the first ever internet domain name registered? A) 1978 B) 1989 C) 1993 D) 1985 | (keep scrolling for the answer) |
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| Dose of Knowledge Answer | D) 1985 A computer systems company in Massachusetts registered the domain ‘Symbolics.com’ on March 15, 1985. Today, the website plays host to the Big Internet Museum. |
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