🤖 Science & Emerging Tech

That'll do, pig

Thursday, Aug 17, 2023

Image: Joe Carrotta/NYU Langone Transplant Institute

Yesterday, two separate teams of US scientists announced breakthroughs in their respective attempts to create genetically modified pig kidneys that function normally when transplanted into human patients.

🧑‍🔬 Here’s what happened: In a peer-reviewed research letter, surgeons from the University of Alabama at Birmingham say a pair of modified pig kidneys transplanted into a brain-dead human patient performed the organ’s two most essential functions – filtering blood and creating urine – for a full week, which the authors describe as a first-of-its-kind occurrence.

Around the same time the UAB letter was published, surgeons at NYU announced one of their modified pig kidneys has been working in a brain-dead human patient for 32 days and counting, the longest period for such an experiment on record (though the results have yet to be peer-reviewed).

  • In both breakthroughs, the scientists involved say more work is needed to conclusively establish whether pig kidneys can be safely used for human transplants.
  • Their research comes more than a year after the first person to receive a genetically modified pig’s heart lived for two months following the groundbreaking transplant.

🇺🇸 Zoom out: Roughly 106,000 Americans are currently on the organ transplant list, and nearly 90% of them need a kidney. An estimated 13 people in the US die each day while waiting for a life-saving kidney transplant.

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